Viện Công Nghiệp Thực Phẩm

Địa chỉ: 301 đường Nguyễn Trãi, phường Thanh Xuân Trung, quận Thanh Xuân, Hà Nội

Điện thoại: 024 38 583 983       Email:,


Hotline: 0243 8584 318

Trung tâm phân tích: 024 3858 2752


17/10/2017 - 07:39


Address: 4th Floor, D building, Food Industries Research Institute, 301 Nguyen Trai Street, Thanh Xuan Trung Ward, Thanh Xuan District, Hanoi, Vietnam.

Telephone: 024 35589004; Cell phone: 0912390182;


ISO/IEC 17025


1. Mission

       Curating the Vietnam Culture Collection of Industrial Microorganisms is our central mission. The center is responsible for the collection, characterization, maintenance, and supply of microbial strains to academic, education institutions, and the industry. Research on technology development and strains improvement through genetic engineering are also conducted. We are aiming at exploring the microbial diversity of Vietnam for the sake of biotechnology. The center has an accredited service laboratory that offers microbial and molecular biology analyses.


2. Staff


    Director: Assoc. Prof. Vu Nguyen Thanh

    Cell phone: 0912390182; Email:


Dinh My Hang

MSc. Biotechnology

Nguyen Thanh Thuy

MSc. Food Technology

Dinh Hoài Thu

MSc. Biotechnology

Dinh Duc Hien

MSc. Biotechnology

Dang Thi Kim Anh

MSc. Biotechnology

Do Thi Yen

MSc. Biotechnology

La Thi My Hanh

MSc. Biotechnology

Cao Xuan Bach

MSc. Biotechnology


3. Laboratories


Maintenance of microorganisms by freeze-drying, storage under deep freeze and in liquid nitrogen

Microbiology and molecular biology laboratories


                                                                         Pilot production facilities


4. Activities

a. Culture collection

      The Collection of Industrial Microorganisms was founded in 1967. Since 1998, the collection has become a member of the National Genetic Resource Network and been funded by the Government. The collection had registered with WFCC in 2013 under WDCM number #1049. Currently, the collection is holding 1410 strains, including 653 yeasts, 304 filamentous fungi, 415 bacteria, and 38 plasmids. These are industrial strains or strains of biotechnological importance. Strains at the collection are maintained by freeze-drying, deep freezing, and in liquid nitrogen. Annually, the collection supplies hundreds of cultures to the industry, academic, and educational institutions.


Images of VCIM strains on frontpage of the International Journal of Systematic   and Evolutionary Microbiology Lipomyces orientalis; Moniliella byzovii


b. Research

The center is conducting basic and applied research in the field of microbiology and biotechnology. We are working on following subjects:


Assessing microbial diversity and functions in traditional fermentations in order to understand and to improve the processes;

Survey for new lignocellulolytic microorganisms for application in bioethanol, animal feed and chemical industries;

Characterization of genetic diversity and application potentials of Moniliella yeasts in Vietnam;

Production of recombinant enzymes for food and feed industries;


c. Education and Training

The center receives PhD, MSc, and postgraduate students from different universities for conducting research activities. The center also organizes seminars, workshops, training programs for local industry.

d. International collaboration

  • Department of Chemical and Biological Engineering, Chalmers University of Technology, Sweden: Enzymes discovery and production in Vietnam for the production of sustainable biofuels and biochemicals.
  • King Mongkut's University, Thailand: UNIDO-GEF project in production of bioethanol from cassava
  • International collections JCM (Japan), CBS (Netherlands), NRRL (USA): Microbial culture exchange.

d. Products and services

  • Microbial strains for food production (ethanol, wine, beer, lactic acid fermentations), reference cultures for analytical laboratories, microbial strains for research and education
  • Microbiological analysis of food and feed (ISO/IEC 17025 accredited)
  • Identification of microorganisms, plant and animal materials by DNA sequencing
  • Training in microbial culture handling, fermentation technology, microbiological analysis and hygiene
  • Selenium yeast for pharmaceutical companies

4. Publication


  • Zoraide Granchi, Sake van Pelt, Vu Nguyen Thanh, Lisbeth Olsson, Silvia Hüttner (2017) Genome Sequence of the Thermophilic Biomass-Degrading Fungus Malbranchea cinnamomea FCH 10.5. Genome Announcements 5: e00779-17.
  • Anasontzis, G.E., Nguyen Thanh Thuy, Dinh Thi My Hang, Han Thu Huong, Dang Tat Thanh, Dinh Duc Hien, Vu Nguyen Thanh, Olsson L (2017). Rice straw hydrolysis using secretomes from novel fungal isolates from Vietnam. Biomass and Bioenergy, 99, 11–20.
  • Vu Nguyen Thanh, Nguyen Thanh Thuy, Nguyen Thuy Chi, Dinh Duc Hien, Bui Thi Viet Ha, Dao Thi Luong, Pham Duc Ngoc, Pham Van Ty (2016) New insight into microbial diversity and functions in traditional Vietnamese alcoholic fermentation. International Journal of Food Microbiology. 232:15-21.
  • Vu Nguyen Thanh, Nguyen Thi Viet Anh (2016). Ethnic Fermented Foods and Beverages of Vietnam. In J. P. Tamang (Ed.), Ethnic Fermented Foods and Alcoholic Beverages of Asia (pp. 383–409). New Delhi: Springer India.
  • Vu Kim Thoa, Nguyen Thi Minh Khanh, Dinh Duc Hien, Le Duc Manh, Vu Nguyen Thanh (2015) Screening of Moniliella yeast with high-level production of erythritol. Proceedings of The IV International Scientific – Practical Conference “Food – Technologies & Health – 2015”. November 20, 2015. Food Research and Development Institute, Plovdiv, Bulgaria.
  • Do Thi Thuy Le, Vu Nguyen Thanh, Phan-Thi Hanh, Cao-Hoang Lan, Ta Thi Minh Ngoc, Yves Waché, Nguyen Thi Hoai Tram (2014) Traditional fermented sausage ‘Nem chua’ as a source of yeast biocatalysts efficient for the production of the aroma compound γ-decalactone. International Journal of Food Science & Technology. Vol. 49, p. 1099-1105.
  • Vu Nguyen Thanh, Tran Thi Thom, Dinh Duc Hien (2013) Moniliella byzovii sp. nov., a chlamydospore-forming black yeast isolated from flowers. International Journal of Systematic and Evolutionary Microbiology. Vol. 63, p. 1192-1196.
  • Vu Nguyen Thanh, Dao Anh Hai, Dinh Duc Hien, Masako Takashima, Marc-André Lachance (2012) Moniliella carnis and Moniliella dehoogii, two new species of black yeasts isolated from meat processing environments. International Journal of Systematic and Evolutionary Microbiology. Vol. 62, p. 3088–3094.
  • Le Thuy Mai, Vu Nguyen Thanh (2010) Cloning of a β-Glucosidase Gene (BGL1) from Traditional Starter Yeast Saccharomycopsis fibuligera BMQ 908 and Expression in Pichia pastoris. International Journal of Biological and Life Sciences 6, 83-87.


  • Đặng Thị Kim Anh, Thân Thị Hương, Nguyễn Thanh Thủy, Đặng Tất Thành, Vũ Nguyên Thành, Lisbeth Cecilia Olsson (2016) Biểu hiện gen mã hóa endo-1,4-β-xylanase chịu nhiệt, hoạt động trong môi trường axit nhằm ứng dụng trong sản xuất thức ăn chăn nuôi. Tạp chí KH Nông nghiệp Việt Nam. 14: 400-408.
  • Lê Thị Kim Tuyến, Bạch Khánh Hòa, Vũ Nguyên Thành, Morgan RD (2015) Biểu hiện và xác định enzyme giới hạn họ MmeI được tìm in silico. Tạp chí Công nghệ Sinh học 13: 831-836.
  • Vũ Nguyên Thành, Nguyễn Quang Thường, Đinh Thị Mỹ Hằng, Đỗ Thị Yến (2014) Sản xuất chế phẩm nấm men giàu selen bằng Saccharomyces pastorianus nhằm ứng dụng trong dược phẩm, thực phẩm chức năng. Tạp chí Khoa học và Công nghệ Việt Nam. 15: 56-60.
  • Nguyễn Thanh Thủy, Nguyễn Thị Hoa Mai, Đinh Thị Mỹ Hằng, Vũ Nguyên Thành (2013) Công nghệ sản xuất isomaltulose từ sucrose sử dụng vi khuẩn Enterobacter sp. ISB-25. Tạp chí Khoa học và Công nghệ 51, 173-184. (ISSN: 0866 708X).
  • Ngô Thanh Xuân, Mai Thị Hằng, Nguyễn Phương Linh, Đinh Thị Mỹ Hằng, Vũ Nguyên Thành (2012) Phân tích trình tự gen (phyA) mã hóa phytase thành thục từ một số chủng Aspergillus niger. Tạp chí Công nghệ Sinh học. 10(1): 115-122. (ISSN: 1811-4989).
  • Nguyễn Thúy Hường, Khuất Thị Thủy, Trần Thúy Anh, Nguyễn Hương Giang, Vũ Nguyên Thành, Nguyễn Thanh Hằng (2011) Lựa chọn chủng nấm men chịu nhiệt và chịu chất sát trùng ứng dụng trong sản xuất cồn từ bột sắn. Tạp chí Khoa học và Công nghệ – Số 80.
  • Vũ Nguyên Thành, Nguyễn Thanh Thủy, Đào Anh Hải, Ninh Thị Huyền, Nguyễn Thị Hương Giang (2011) Phân lập và sàng lọc nấm men có khả năng lên men D-xylose. Tạp chí Công nghệ Sinh học 9(4): 493-501. (ISSN: 1811-4989).
  • Nguyễn Thanh Thủy, Dương Anh Tuấn, Vũ Nguyên Thành (2011) Tinh chế peroxidase từ củ cài trắng Rhaphanus sativus var hortensis và ứng dụng trong xét nghiệm ethanol. Tạp chí Công nghệ Sinh học. 9(1): 113-118. (ISSN: 1811-4989).
  • Nguyễn Văn Hoan, Lê Hữu Điển, Lê Minh Hà,Đào Anh Hải, Kiều Văn Hải, Vũ Nguyên Thành (2010) Nghiên cứu thiết kế hệ thống thiết bị sản xuất cồn từ bã mía. Tạp chí Khoa học và Công nghệ, 48-4A, 490-497. (ISSN: 0866 708X).
  • Cao Văn Thu, Bui Viet Ha, Quách Thị Lê Hà, Nguyễn Hồng Hạnh, Nguyễn Thị Thuý Hiền, Phan Văn Kiệm, Võ Thị Linh, Vũ Nguyên Thành, Võ Thị Thu Thuỷ (2010) Nghiên cứu lên men sinh tổng hợp kháng sinh nhờ Streptomyces 15.29 - Streptomyces microflavus. Tạp chí Khoa học và Công nghệ (Viện Khoa học và Công nghệ Việt Nam) T. 48, S. 5. Tr. 105-111. (ISSN: 0866 708X).


  • National Office of Intellectual Property of Viet Nam (NOIP): #2-0001450 “Yeast strains Pichia pastoris CNTP 9056 and Pichia pastoris CNTP 9057 producing recombinant thermostable phytase”. Applied 2012; Accepted 2013; Awarded: 2016. Inventors: Vu Nguyen Thanh, Dinh Thi My Hang, Tran Thi Thanh Tam, Dang Thi Kim Anh. Assignee: Food Industries Research Institute.
  • Patent Application #2-2016-00223 “Yeast strains Pichia pastoris producing recombinant thermostable xylanase”. Applied 2016; Accepted 2016. Inventors: Vu Nguyen Thanh, Dang Thi Kim Anh, Dinh Thi My Hang, Nguyen Thanh Thuy, Dang Tat Thanh. Assignee: Food Industries Research Institute.


5. Images on activities of Center for Industrial Microbiology


Isolation of lignocellulolytic fungi from tropical forest


     Selen yeasts



Microbial strains


Nguyen Thanh Thuy at the Department of Chemical and Biological Engineering,

Chalmers University of Technology, Sweden


Workshop on lignocellulolytic enzymes at Ba Vi, Hanoi, Vietnam (1-2/11/2013)





                                                                                                   CENTER FOR INDUSTRIAL MICROBIOLOGY

                                                                                                   4th Floor, D building, Food Industries Research Institute

                                                                                                   301 Nguyen Trai, Thanh Xuan, Hanoi, Vietnam

                                                                                                   Telephone/ cell phone  024 35589004; 0912390182;





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